The Role of Genetic Mutations in Disease Pathogenesis

Abstract

Genetic mutations are alterations in the DNA sequence that can disrupt normal cellular processes, leading to a variety of diseases. This article explores the role of genetic mutations in disease pathogenesis, focusing on the mechanisms by which mutations contribute to the development of both hereditary and acquired diseases. It discusses the different types of genetic mutations, including point mutations, insertions, deletions, and chromosomal abnormalities, and their effects on gene expression, protein function, and cellular behavior. The article also highlights the use of modern genetic tools in understanding disease mechanisms and developing targeted therapies.