Abstract
Pharmacokinetic modeling plays a critical role in understanding the absorption, distribution, metabolism, and excretion (ADME) of drugs. By simulating these processes, pharmacokinetic models offer valuable insights that can be applied to drug dosage optimization, enhancing therapeutic efficacy and minimizing side effects. This article explores the principles of pharmacokinetic modeling, its applications in drug development, and the optimization of drug dosages in clinical settings. The article also highlights advancements in pharmacokinetic models, including population pharmacokinetics and physiologically-based pharmacokinetic (PBPK) modeling, and discusses their contributions to individualized medicine. The role of these models in improving patient outcomes through optimal drug dosing regimens is emphasized.
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