Abstract
Cytokines are key regulators of immune responses and play a significant role in modulating drug efficacy and toxicity. They can influence the pharmacokinetics and pharmacodynamics of drugs, particularly in inflammatory and autoimmune conditions. This article explores the mechanisms by which cytokines alter drug response, their impact on drug-metabolizing enzymes and transporters, and their role in therapeutic resistance and adverse reactions. Understanding cytokine-drug interactions is crucial for optimizing treatment strategies, especially in personalized medicine.
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