Abstract
Genetic disorders result from mutations in one or more genes that affect normal biological processes, leading to a wide range of diseases. Bioinformatics has become a crucial tool in identifying genetic mutations, understanding their molecular mechanisms, and developing therapeutic strategies for genetic disorders. This article reviews the bioinformatics approaches used to target genetic disorders, including genome-wide association studies (GWAS), mutation prediction tools, gene editing technologies, and personalized medicine. We also discuss the challenges and future directions in bioinformatics research related to genetic disorders.
All articles published in the American Journal of Bioinformatics (AJB) are licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). Under this license, authors retain full copyright of their work and grant permission to anyone to:
-
Share — copy and redistribute the material in any medium or format
-
Adapt — remix, transform, and build upon the material for any purpose, even commercially
Conditions:
-
Attribution: Appropriate credit must be given to the original author(s) and the source, a link to the license must be provided, and any changes made must be indicated.
-
No additional restrictions: You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
This open-access license ensures that scholarly work published in AJB is freely accessible and usable, promoting knowledge dissemination and academic collaboration worldw